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Viral Integration Site DataBase
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TVIS30009866
Basic Information
VIS ID
TVIS30009866
Fusion event
HIV-NOTCH1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q34.3
Reference genome
GRCh37/hg19
Start
139437052/136542600 (Hg38)
End
139437052/136542600 (Hg38)
Orient
-
Location type
Intronic
Target gene
NOTCH1
miRNAs that regulate target gene
hsa-mir-27b-3p
;
hsa-mir-24-3p
;
hsa-mir-23b-3p
;
hsa-mir-34a-5p
;
hsa-mir-30a-5p
;
hsa-mir-326
;
hsa-mir-129-5p
;
hsa-mir-144-3p
;
hsa-mir-449a
;
hsa-mir-34b-3p
;
hsa-mir-34c-5p
;
hsa-mir-10b-5p
;
hsa-mir-181a-5p
;
hsa-mir-30b-5p
;
hsa-mir-139-5p
;
hsa-mir-30c-5p
;
hsa-mir-30d-5p
;
hsa-mir-30e-5p
;
hsa-mir-200b-3p
;
hsa-mir-200c-3p
;
hsa-mir-5006-3p
;
hsa-mir-4755-5p
;
hsa-mir-519e-5p
;
hsa-mir-515-5p
;
hsa-mir-211-5p
;
hsa-mir-204-5p
;
hsa-mir-623
;
hsa-mir-5695
;
hsa-mir-519d-5p
;
hsa-mir-5088-3p
;
hsa-mir-335-3p
;
hsa-mir-627-3p
;
hsa-mir-6761-3p
;
hsa-mir-4793-5p
;
hsa-mir-5196-3p
;
hsa-mir-1277-3p
;
hsa-mir-363-3p
;
hsa-mir-9-5p
;
hsa-mir-410-3p
;
hsa-mir-101-3p
;
hsa-mir-935
;
hsa-mir-30a-3p
;
hsa-mir-146a-5p
;
hsa-mir-296-5p
Nearest miRNA
hsa-let-7a-1/Upstream/22974; hsa-mir-126/Downstream/3573;
Nearest TSS
ENST00000422679/Upstream/18702;
ENST00000439501/Downstream/281;
Nearest CpG islands
None/Target,
chr9-CpG: 64/Upstream/8525
,
chr9-CpG: 263/Downstream/1989
Nearest cancer related gene
NOTCH1
(OG, No orient, 0)
Upstream sequence
CGTCCGTGCGGCTTCTGCAGAGGGAGAAGGGGGCCCCaaaaagcaaaaaaaaaaaaaaaaaaaaaaGTAGTGCGCATTCATTAGTGTCTGACAAAGACAC
Downstream sequence
AATCGGCTTTGTCCATTAAACTGCTCACAGACCTGCTTAATTGGCTTCAGTTTGGGGAGGGTGGGGGCCGGGGAGGGAGGGGGCCTGCTGCCCACAGGCT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Central Memory CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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