Basic Information
VIS ID
TVIS30009912
Fusion event
HIV-POLA1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
p22.11
Reference genome
GRCh37/hg19
Start
24809033/24790916 (Hg38)
End
24809033/24790916 (Hg38)
Orient
-
Location type
Intronic
Target gene
POLA1
miRNAs that regulate target gene
hsa-mir-193b-3p ; hsa-mir-124-3p ; hsa-mir-26b-5p ; hsa-mir-6885-3p ; hsa-mir-6882-3p
Nearest miRNA
hsa-mir-23c/Upstream/4773729; hsa-let-7f-2/Downstream/3704639;
Nearest TSS
ENST00000429181/Upstream/45413; ENST00000494204/Downstream/21914;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/96749, chrX-CpG: 290/Downstream/211204
Upstream sequence
TATGAGAAATTAGTGTCATATCCTGCAAGTGTATATGAATATGTGCACTCATTTTACGTGTATATACAGCCCCCACTCATTtatttatgtatatgtatat
Downstream sequence
atatatatatatatatatatatataAAACATTTAACCTAAGAAGAACTTGCAATTGTTAAGCTGCTCAAGAACTTTCAGAGGTTCTAACACAGTTGCACA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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