Basic Information
VIS ID
TVIS30009951
Fusion event
HIV-HDAC8 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
71777222/72557372 (Hg38)
End
71777222/72557372 (Hg38)
Orient
+
Location type
Intronic
Target gene
HDAC8
miRNAs that regulate target gene
hsa-mir-449a ; hsa-mir-218-5p ; hsa-mir-216b-5p ; hsa-mir-455-3p
Nearest miRNA
hsa-let-7f-2/Upstream/2534449; hsa-mir-105-1/Downstream/1661005;
Nearest TSS
ENST00000429181/Upstream/94928; ENST00000420998/Downstream/15255;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/249923, chrX-CpG: 32/Downstream/123232
Upstream sequence
cattctccaagacagaccatatgataggccacaaaacaagtctcacttaagaaaatctttaacaagccttgattttaaaaatcaaaattatatcaagtac
Downstream sequence
tctctcagatcacagtggaataaaattagaaataaactccaaaaggcaccctcaaaaccatgcaaatacatggcaattaaataacctgcttctgaatgaa
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate