Basic Information
VIS ID
TVIS30010057
Fusion event
HIV-KDM1A integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.12
Reference genome
GRCh37/hg19
Start
23371756/23045263 (Hg38)
End
23371756/23045263 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
KDM1A
miRNAs that regulate target gene
hsa-mir-137 ; hsa-mir-155-5p ; hsa-mir-500a-5p ; hsa-mir-23b-3p ; hsa-mir-329-3p ; hsa-mir-708-5p
Nearest miRNA
hsa-mir-12136/Upstream/891; hsa-mir-101-1/Downstream/883807;
Nearest TSS
ENST00000473358/Upstream/25770; ENST00000481879/Downstream/5162;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/25079, chr1-CpG: 92/Downstream/122483
Upstream sequence
TAACGTATCTGGATTTCATCCTTTGTCTCTTGAAGGATGTTTTTGTTCCAGTTGCTCAAAGCTGGTTTATAGATACGTTTTGATAGAATTGGAATAGGCA
Downstream sequence
CTACTTCACTTTTGGAGGTTGTCACTTTTCAACTGTCTTAAGTCTACTTTAAAATTATTTGTTTTGCAGTTTGCATATAACAGGTCCTGGGACTGTTTCT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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