Basic Information
VIS ID
TVIS30010075
Fusion event
HIV-TUT4 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p32.3
Reference genome
GRCh37/hg19
Start
52961730/52496058 (Hg38)
End
52961730/52496058 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1B
Target gene
TUT4
miRNAs that regulate target gene
hsa-mir-196a-5p ; hsa-let-7b-5p ; hsa-mir-26a-5p ; hsa-mir-4791 ; hsa-mir-3201 ; hsa-mir-203a-3p ; hsa-mir-216b-5p
Nearest miRNA
hsa-mir-12136/Upstream/659656; hsa-mir-101-1/Downstream/1558021;
Nearest TSS
ENST00000473358/Upstream/27568; ENST00000607321/Downstream/29872;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/91425, chr1-CpG: 115/Downstream/56528
Upstream sequence
TCAGTTAATTCTGTAAACCTAAAACCCAAAACACTGTGGTTCTCAAGAGTTTATAGAAAAAAAAGAAAAGCAGTAACACACTACTTACAGCTTTCCCAGA
Downstream sequence
CTATGAAACATGTTATTCCAAAAATCATAATAAGGCAAATGTTAAAAGGATCTCACCAGAGGCCAATTTGAAAATAATATGATTGGGACAGATCAAGAAG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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