Basic Information
VIS ID
TVIS30010083
Fusion event
HIV-ZZZ3 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p31.1
Reference genome
GRCh37/hg19
Start
78069418/77603733 (Hg38)
End
78069418/77603733 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1L
Target gene
ZZZ3
miRNAs that regulate target gene
hsa-mir-548aw ; hsa-mir-6071 ; hsa-mir-6828-3p ; hsa-mir-7158-5p ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-3182 ; hsa-mir-767-3p ; hsa-mir-5688 ; hsa-mir-495-3p
Nearest miRNA
hsa-mir-101-1/Upstream/543531; hsa-mir-11399/Downstream/7530061;
Nearest TSS
ENST00000473358/Upstream/18674; ENST00000476203/Downstream/28188;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/321194, chr1-CpG: 94/Downstream/78799
Upstream sequence
AATCTACTAAAACACTCTCTAAATGCAGACCTAGGAATCTACATTTTTAACAGGACAAGGCAAAATTTTTTTATACTCAAGGTCTAATACATAAGGTAAG
Downstream sequence
TTTTATATAAAGATTATGAGCCACTGATTCGAAGAGCTTCTTAAAAAAAAAGAGGAATATTTCAGATCTCAGATCTTATTTCTGACATAAAACTTTTAAC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate