Basic Information
VIS ID
TVIS30010090
Fusion event
HIV-MAN1A2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p12
Reference genome
GRCh37/hg19
Start
117982006/117439384 (Hg38)
End
117982006/117439384 (Hg38)
Orient
-
Location type
Intronic
Target gene
MAN1A2
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-142-3p ; hsa-mir-30a-5p ; hsa-mir-130b-3p ; hsa-mir-541-5p ; hsa-mir-3653-3p ; hsa-mir-6869-5p ; hsa-mir-496 ; hsa-mir-8087 ; hsa-mir-7161-5p ; hsa-mir-548u ; hsa-mir-4455 ; hsa-mir-640 ; hsa-mir-6867-5p ; hsa-mir-4286 ; hsa-mir-4262 ; hsa-mir-216b-3p ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181b-5p ; hsa-mir-181a-5p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-3976 ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-1277-5p ; hsa-mir-3125 ; hsa-mir-3916 ; hsa-mir-4662a-3p ; hsa-mir-4662a-5p ; hsa-mir-6124 ; hsa-mir-6832-5p ; hsa-mir-6859-5p ; hsa-mir-8081
Nearest miRNA
hsa-mir-101-1/Upstream/344656; hsa-mir-1182/Downstream/28411203;
Nearest TSS
ENST00000473358/Upstream/18787; ENST00000421535/Downstream/57396;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/71561, chr1-CpG: 135/Downstream/165952
Upstream sequence
gagatagggagccatttgagggttctaaactgttgacttctatttaacactcccacattgactgctagattgagaataggctgcaAAAATATTATCTTAG
Downstream sequence
TAACTTAAGTACTCTAATAGAGAAAACAGGCATAAGAAGCATATATAGATCCTAATGTCACTTCCCTCCTCAAGAAACTACAGTGGTTCTATGTTACCTA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate