Basic Information
VIS ID
TVIS30010146
Fusion event
HIV-MINPP1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
89308889/87549132 (Hg38)
End
89308889/87549132 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10D
Target gene
MINPP1
miRNAs that regulate target gene
hsa-mir-374b-5p ; hsa-mir-340-5p ; hsa-mir-1-3p ; hsa-mir-454-5p ; hsa-mir-4670-3p
Nearest miRNA
hsa-mir-1265/Upstream/45178; hsa-mir-107/Downstream/1514203;
Nearest TSS
ENST00000439456/Upstream/28017; ENST00000438082/Downstream/56892;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/43518, chr10-CpG: 65/Downstream/110457
Upstream sequence
ATATATAAACTTCCTTGATTTCCCATAAAACTTCCAGTAAGCATTTTTAAGTATAATTTTCCTCAAATTTCTTCTGAAGAATTCACTGATTTTAACATAT
Downstream sequence
CACTGACAGTAAGGCAGTAAAAAAAGGGGGGAAGGTGTTTACTGCCTTTTGTATAAACCCAAGGAACCTTGAAATTTACAACTTAAATTTGAGTCACAGT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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