Basic Information
VIS ID
TVIS30010156
Fusion event
HIV-ATE1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q26.13
Reference genome
GRCh37/hg19
Start
123620490/121860975 (Hg38)
End
123620490/121860975 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10D ; FRA10F ; FRA10A ; FRA10B
Target gene
ATE1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-130b-3p ; hsa-let-7b-5p
Nearest miRNA
hsa-mir-107/Upstream/1902383; hsa-mir-202/Downstream/555990;
Nearest TSS
ENST00000439456/Upstream/70749; ENST00000618971/Downstream/41563;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/251756, chr10-CpG: 125/Downstream/66482
Upstream sequence
TATGCTTATGTGAGCCCTTACTTAACGTCGTCAGTTCAATTTGAGATTCCTGCTTTTACAATATTTCTTATGAGGGAAAAATACATCCCACAGTGACAAC
Downstream sequence
CCAGACTGAGAACTCAATGACTGCCAACATCAAACAAGACTGATGTCCCCATGGAAACTAATCCACCCCAGGATTTTCTATTCAAACATTTTCTGAAGCA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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