Basic Information
VIS ID
TVIS30010171
Fusion event
HIV-PIK3C2A integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p15.1
Reference genome
GRCh37/hg19
Start
17174972/17153425 (Hg38)
End
17174972/17153425 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA11C ; FRA11I
Target gene
PIK3C2A
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-124-3p ; hsa-mir-22-3p ; hsa-mir-21-5p ; hsa-let-7i-5p ; hsa-mir-182-5p ; hsa-mir-26a-5p ; hsa-mir-544a ; hsa-mir-6878-3p ; hsa-mir-378a-5p ; hsa-mir-6744-3p ; hsa-mir-4757-5p ; hsa-mir-6778-3p ; hsa-mir-4454 ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-3653-5p ; hsa-mir-150-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-212-5p ; hsa-mir-1224-3p ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-6813-3p ; hsa-mir-186-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-518a-5p ; hsa-mir-218-1-3p
Nearest miRNA
hsa-mir-210/Upstream/1183804; hsa-let-7a-2/Downstream/1234362;
Nearest TSS
ENST00000527297/Upstream/75638; ENST00000620945/Downstream/16316;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/75466, chr11-CpG: 68/Downstream/54039
Upstream sequence
taaggaggctgaggcaggagaatcgcttgaacctggaaggcaaaggttgcagtgaactgagatcgcaccactgcattccaccctgggcaacaagagtgaa
Downstream sequence
aactccatttcaaaaaaaaaaaaaaagaaCCTTTTCAGCACCTGTAACTAGTAGATATAGCAAGCTTTGTCAATTATGATAGGTGTAAAAGGAAAGAAAT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate