Basic Information
VIS ID
TVIS30010175
Fusion event
HIV-CAT integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p13
Reference genome
GRCh37/hg19
Start
34474985/34453438 (Hg38)
End
34474985/34453438 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA11E
Target gene
CAT
miRNAs that regulate target gene
hsa-mir-30b-5p ; hsa-mir-155-5p ; hsa-mir-30a-5p ; hsa-mir-181b-5p
Nearest miRNA
hsa-mir-210/Upstream/5975890; hsa-let-7a-2/Downstream/488399;
Nearest TSS
ENST00000527297/Upstream/14513; ENST00000528104/Downstream/2711;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/14128, chr11-CpG: 98/Downstream/462343
Nearest cancer related gene
CAT(TSG, No orient, 0)
Upstream sequence
CTGGCTTTACTAATCATCCCCCATTCATCGGCCTTAAatgatgatgatgatgatgatAGATAGCTAGCAACATTGTCAGTTGATATTTAGCAGTAGTAAG
Downstream sequence
GATGAAAGTCTGTAGTGTAAGGTAAAGCTCTGTATTAAGGAAGTGGGGGGAAAGTAGTACCAAACAAATTTGCTATGCAAATAAATTTTGAATAACAAAT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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