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Viral Integration Site DataBase
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TVIS30010176
Basic Information
VIS ID
TVIS30010176
Fusion event
HIV-CD44 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p13
Reference genome
GRCh37/hg19
Start
35182331/35160784 (Hg38)
End
35182331/35160784 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA11E
Target gene
CD44
miRNAs that regulate target gene
hsa-mir-328-3p
;
hsa-mir-373-3p
;
hsa-mir-199a-3p
;
hsa-mir-520c-3p
;
hsa-mir-34a-5p
;
hsa-mir-608
;
hsa-mir-330-3p
;
hsa-mir-216a-5p
;
hsa-mir-708-5p
;
hsa-mir-199a-5p
;
hsa-mir-1-3p
;
hsa-mir-30a-5p
;
hsa-mir-16-5p
;
hsa-mir-744-5p
;
hsa-mir-320a
;
hsa-mir-15b-5p
;
hsa-mir-143-3p
;
hsa-mir-145-5p
;
hsa-mir-218-5p
;
hsa-mir-4776-3p
;
hsa-mir-4642
;
hsa-mir-192-3p
;
hsa-mir-6826-3p
;
hsa-mir-3121-5p
;
hsa-mir-3667-3p
;
hsa-mir-6734-3p
;
hsa-mir-6756-3p
;
hsa-mir-3127-3p
;
hsa-mir-4793-5p
;
hsa-mir-5196-3p
;
hsa-mir-942-3p
;
hsa-mir-4802-3p
;
hsa-mir-4753-3p
;
hsa-mir-664b-3p
;
hsa-mir-579-3p
;
hsa-mir-5696
;
hsa-mir-130b-5p
;
hsa-mir-552-5p
;
hsa-mir-211-5p
;
hsa-mir-204-5p
;
hsa-mir-6716-5p
;
hsa-mir-302d-5p
;
hsa-mir-6832-3p
;
hsa-mir-302b-5p
;
hsa-mir-6866-3p
;
hsa-mir-188-5p
;
hsa-mir-520a-3p
;
hsa-mir-125b-5p
;
hsa-mir-328-5p
;
hsa-mir-1321
;
hsa-mir-149-3p
;
hsa-mir-197-5p
;
hsa-mir-3132
;
hsa-mir-3175
;
hsa-mir-3529-5p
;
hsa-mir-379-5p
;
hsa-mir-4270
;
hsa-mir-4441
;
hsa-mir-4524b-3p
;
hsa-mir-4728-5p
;
hsa-mir-4739
;
hsa-mir-4756-5p
;
hsa-mir-6731-5p
;
hsa-mir-6754-5p
;
hsa-mir-6755-5p
;
hsa-mir-6785-5p
;
hsa-mir-6883-5p
;
hsa-mir-7106-5p
;
hsa-mir-765
;
hsa-mir-8085
Nearest miRNA
hsa-mir-1343/Upstream/218864; hsa-let-7a-2/Downstream/849314;
Nearest TSS
ENST00000527297/Upstream/21478;
ENST00000531118/Downstream/15791;
Nearest CpG islands
None/Target,
chr11-CpG: 30/Upstream/21331
,
chr11-CpG: 143/Downstream/258090
Nearest cancer related gene
CD44
(TSG, No orient, 0)
Upstream sequence
gcttatcagtaagaagcctgatattaaaactccaggtcactagaccttcaacctaatgttcttcccactaaaccaAGTTaacatttattgtacaccatac
Downstream sequence
taaatggcagacactggggacacaaagatgaataaggcatggtcccAGTGGAACCCACTTTGGTTATATGGGTTAGGACACTTGAGGCAGGATCCTCCTT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Jurkat CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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