Basic Information
VIS ID
TVIS30010203
Fusion event
HIV-FCHSD2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q13.4
Reference genome
GRCh37/hg19
Start
72817105/73106060 (Hg38)
End
72817105/73106060 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA11H
Target gene
FCHSD2
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-7159-3p ; hsa-mir-4668-5p ; hsa-mir-210-3p ; hsa-mir-548o-3p ; hsa-mir-1323 ; hsa-mir-4272 ; hsa-mir-3613-3p ; hsa-mir-6074 ; hsa-mir-3622a-5p ; hsa-mir-548an ; hsa-mir-4482-3p ; hsa-mir-4474-5p ; hsa-mir-4662a-5p ; hsa-mir-6791-3p ; hsa-mir-6829-3p ; hsa-mir-449b-3p ; hsa-mir-27b-3p ; hsa-mir-27a-3p
Nearest miRNA
hsa-mir-10392/Upstream/322468; hsa-let-7a-2/Downstream/1293177;
Nearest TSS
ENST00000527297/Upstream/117048; ENST00000541254/Downstream/34001;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/283331, chr11-CpG: 192/Downstream/35071
Upstream sequence
CTTCACAGGTCTGTATACAAGCTAATATTTGCATCCAAGGATTTCCAgaattattcagaatcataaaatcagagaactgggatgaactttagaaattatg
Downstream sequence
tggagaacatctgtggttcacagaaaaagtaactgaggccaaaagTAAATAATTAATTTTACAAAATCTTGAAATTTCCCTTATTGGACCTCGGAGGAGT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate