Basic Information
VIS ID
TVIS30010224
Fusion event
HIV-KMT2A integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q23.3
Reference genome
End
118339539/118468824 (Hg38)
Orient
+
Location type
Exonic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-128b ; hsa-mir-335-5p ; hsa-mir-16-5p ; hsa-let-7d-5p ; hsa-mir-320b ; hsa-mir-1227-3p ; hsa-mir-484 ; hsa-mir-320a ; hsa-mir-193a-3p ; hsa-mir-17-5p ; hsa-mir-199a-3p ; hsa-mir-183-3p ; hsa-mir-199b-3p ; hsa-mir-142-3p ; hsa-mir-616-3p ; hsa-mir-2052 ; hsa-mir-3127-5p ; hsa-mir-3129-5p ; hsa-mir-3153 ; hsa-mir-4452 ; hsa-mir-4632-5p ; hsa-mir-4699-3p ; hsa-mir-4436b-3p ; hsa-mir-6733-5p ; hsa-mir-6735-5p ; hsa-mir-6739-5p ; hsa-mir-6879-5p ; hsa-mir-7843-5p ; hsa-mir-27a-3p ; hsa-mir-30a-3p ; hsa-mir-30d-3p ; hsa-mir-27b-3p ; hsa-mir-30e-3p ; hsa-mir-5681a ; hsa-mir-3918 ; hsa-mir-106a-3p ; hsa-mir-129-1-3p ; hsa-mir-129-2-3p ; hsa-mir-450b-5p ; hsa-mir-3121-5p ; hsa-mir-302c-3p ; hsa-mir-520f-3p ; hsa-mir-374a-5p ; hsa-mir-218-5p ; hsa-mir-636 ; hsa-mir-450a-1-3p ; hsa-mir-4668-5p ; hsa-mir-5189-3p ; hsa-mir-6895-5p ; hsa-mir-6832-3p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-4753-3p ; hsa-mir-130b-5p ; hsa-mir-1250-3p ; hsa-mir-3942-3p ; hsa-mir-302c-5p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-3143 ; hsa-mir-4670-3p ; hsa-mir-6759-3p ; hsa-mir-6719-3p ; hsa-mir-4526 ; hsa-mir-3660 ; hsa-mir-6730-3p ; hsa-mir-624-3p ; hsa-mir-1293 ; hsa-mir-185-3p ; hsa-mir-30c-1-3p ; hsa-mir-30c-2-3p ; hsa-mir-3184-5p ; hsa-mir-363-5p ; hsa-mir-423-5p ; hsa-mir-4483 ; hsa-mir-4675 ; hsa-mir-4741 ; hsa-mir-541-3p ; hsa-mir-6085 ; hsa-mir-6134 ; hsa-mir-654-5p ; hsa-mir-671-5p ; hsa-mir-6716-5p ; hsa-mir-6731-5p ; hsa-mir-6743-3p ; hsa-mir-6745 ; hsa-mir-6748-5p ; hsa-mir-6756-5p ; hsa-mir-6766-5p ; hsa-mir-6769a-5p ; hsa-mir-6769b-5p ; hsa-mir-6788-5p ; hsa-mir-6813-5p ; hsa-mir-6871-5p ; hsa-mir-6873-5p ; hsa-mir-6878-5p ; hsa-mir-7974 ; hsa-mir-8085 ; hsa-mir-92a-2-5p ; hsa-mir-9500 ; hsa-mir-1178-5p ; hsa-mir-1180-3p ; hsa-mir-1301-3p ; hsa-mir-26a-1-3p ; hsa-mir-26a-2-3p ; hsa-mir-3926 ; hsa-mir-4660 ; hsa-mir-4778-5p ; hsa-mir-5047 ; hsa-mir-6850-3p
Nearest miRNA
hsa-mir-10392/Upstream/5018736; hsa-let-7a-2/Downstream/175176;
Nearest cancer related gene
KMT2A(OG, No orient, 0)
Upstream sequence
TGTATGCACGTTTTTGCTTCTGATTTTAAAATAATTTTCCTTTGTTGTAGGATGAGCAATTCTTAGGTTTTGGCTCAGATGAAGAAGTCAGAGTGCGAAG
Downstream sequence
TCCCACAAGGTCTCCTTCAGGTACGGCCAATTAAGTGCATGGTGCCTTTTAAGTTTTGTTTGTTAGGAGATTGTGGCTTCCTCTTGCCTTCTTTACATGT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate