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TVIS30010224
Basic Information
VIS ID
TVIS30010224
Fusion event
HIV-KMT2A integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
118339539/118468824 (Hg38)
End
118339539/118468824 (Hg38)
Orient
+
Location type
Exonic
Fragile sites / regions
FRA11B
Target gene
KMT2A
miRNAs that regulate target gene
hsa-mir-128b
;
hsa-mir-335-5p
;
hsa-mir-16-5p
;
hsa-let-7d-5p
;
hsa-mir-320b
;
hsa-mir-1227-3p
;
hsa-mir-484
;
hsa-mir-320a
;
hsa-mir-193a-3p
;
hsa-mir-17-5p
;
hsa-mir-199a-3p
;
hsa-mir-183-3p
;
hsa-mir-199b-3p
;
hsa-mir-142-3p
;
hsa-mir-616-3p
;
hsa-mir-2052
;
hsa-mir-3127-5p
;
hsa-mir-3129-5p
;
hsa-mir-3153
;
hsa-mir-4452
;
hsa-mir-4632-5p
;
hsa-mir-4699-3p
;
hsa-mir-4436b-3p
;
hsa-mir-6733-5p
;
hsa-mir-6735-5p
;
hsa-mir-6739-5p
;
hsa-mir-6879-5p
;
hsa-mir-7843-5p
;
hsa-mir-27a-3p
;
hsa-mir-30a-3p
;
hsa-mir-30d-3p
;
hsa-mir-27b-3p
;
hsa-mir-30e-3p
;
hsa-mir-5681a
;
hsa-mir-3918
;
hsa-mir-106a-3p
;
hsa-mir-129-1-3p
;
hsa-mir-129-2-3p
;
hsa-mir-450b-5p
;
hsa-mir-3121-5p
;
hsa-mir-302c-3p
;
hsa-mir-520f-3p
;
hsa-mir-374a-5p
;
hsa-mir-218-5p
;
hsa-mir-636
;
hsa-mir-450a-1-3p
;
hsa-mir-4668-5p
;
hsa-mir-5189-3p
;
hsa-mir-6895-5p
;
hsa-mir-6832-3p
;
hsa-mir-6809-3p
;
hsa-mir-6833-3p
;
hsa-mir-4768-5p
;
hsa-mir-4753-3p
;
hsa-mir-130b-5p
;
hsa-mir-1250-3p
;
hsa-mir-3942-3p
;
hsa-mir-302c-5p
;
hsa-mir-215-5p
;
hsa-mir-192-5p
;
hsa-mir-3143
;
hsa-mir-4670-3p
;
hsa-mir-6759-3p
;
hsa-mir-6719-3p
;
hsa-mir-4526
;
hsa-mir-3660
;
hsa-mir-6730-3p
;
hsa-mir-624-3p
;
hsa-mir-1293
;
hsa-mir-185-3p
;
hsa-mir-30c-1-3p
;
hsa-mir-30c-2-3p
;
hsa-mir-3184-5p
;
hsa-mir-363-5p
;
hsa-mir-423-5p
;
hsa-mir-4483
;
hsa-mir-4675
;
hsa-mir-4741
;
hsa-mir-541-3p
;
hsa-mir-6085
;
hsa-mir-6134
;
hsa-mir-654-5p
;
hsa-mir-671-5p
;
hsa-mir-6716-5p
;
hsa-mir-6731-5p
;
hsa-mir-6743-3p
;
hsa-mir-6745
;
hsa-mir-6748-5p
;
hsa-mir-6756-5p
;
hsa-mir-6766-5p
;
hsa-mir-6769a-5p
;
hsa-mir-6769b-5p
;
hsa-mir-6788-5p
;
hsa-mir-6813-5p
;
hsa-mir-6871-5p
;
hsa-mir-6873-5p
;
hsa-mir-6878-5p
;
hsa-mir-7974
;
hsa-mir-8085
;
hsa-mir-92a-2-5p
;
hsa-mir-9500
;
hsa-mir-1178-5p
;
hsa-mir-1180-3p
;
hsa-mir-1301-3p
;
hsa-mir-26a-1-3p
;
hsa-mir-26a-2-3p
;
hsa-mir-3926
;
hsa-mir-4660
;
hsa-mir-4778-5p
;
hsa-mir-5047
;
hsa-mir-6850-3p
Nearest miRNA
hsa-mir-10392/Upstream/5018736; hsa-let-7a-2/Downstream/175176;
Nearest TSS
ENST00000527297/Upstream/32062;
ENST00000420751/Downstream/13007;
Nearest CpG islands
None/Target,
chr11-CpG: 30/Upstream/31834
,
chr11-CpG: 106/Downstream/61696
Nearest cancer related gene
KMT2A
(OG, No orient, 0)
Upstream sequence
TGTATGCACGTTTTTGCTTCTGATTTTAAAATAATTTTCCTTTGTTGTAGGATGAGCAATTCTTAGGTTTTGGCTCAGATGAAGAAGTCAGAGTGCGAAG
Downstream sequence
TCCCACAAGGTCTCCTTCAGGTACGGCCAATTAAGTGCATGGTGCCTTTTAAGTTTTGTTTGTTAGGAGATTGTGGCTTCCTCTTGCCTTCTTTACATGT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Jurkat CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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