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TVIS30010249
Basic Information
VIS ID
TVIS30010249
Fusion event
HIV-KMT2D integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q13.12
Reference genome
GRCh37/hg19
Start
49440449/49046666 (Hg38)
End
49440449/49046666 (Hg38)
Orient
-
Location type
Exonic
Fragile sites / regions
FRA12A
Target gene
KMT2D
miRNAs that regulate target gene
hsa-mir-130b-3p
;
hsa-mir-186-5p
;
hsa-mir-9-5p
;
hsa-mir-34a-5p
;
hsa-mir-93-5p
;
hsa-mir-1229-3p
;
hsa-mir-1224-3p
;
hsa-mir-760
;
hsa-mir-877-5p
;
hsa-mir-744-5p
;
hsa-mir-766-3p
;
hsa-mir-615-3p
;
hsa-mir-92b-3p
;
hsa-mir-18a-3p
;
hsa-mir-196b-5p
;
hsa-mir-106b-5p
;
hsa-mir-320a
;
hsa-mir-125b-5p
;
hsa-mir-15b-5p
;
hsa-mir-222-3p
;
hsa-mir-30c-5p
;
hsa-mir-92a-3p
;
hsa-mir-27a-3p
;
hsa-mir-218-5p
;
hsa-mir-30c-1-3p
;
hsa-mir-4260
;
hsa-mir-4665-5p
;
hsa-mir-1275
;
hsa-mir-1227-5p
;
hsa-mir-3147
;
hsa-mir-4447
;
hsa-mir-4472
;
hsa-mir-1294
;
hsa-mir-92a-2-5p
;
hsa-mir-5010-5p
;
hsa-mir-4525
;
hsa-mir-625-5p
;
hsa-mir-486-3p
;
hsa-mir-8085
;
hsa-mir-6731-5p
;
hsa-mir-6134
;
hsa-mir-3616-3p
;
hsa-mir-296-3p
;
hsa-mir-7843-5p
;
hsa-mir-6879-5p
;
hsa-mir-6735-5p
;
hsa-mir-4632-5p
;
hsa-mir-4436b-3p
;
hsa-mir-5197-3p
;
hsa-mir-449a
;
hsa-mir-34c-5p
;
hsa-mir-449b-5p
;
hsa-mir-6741-5p
;
hsa-mir-6759-5p
;
hsa-mir-6793-5p
;
hsa-mir-6748-5p
;
hsa-mir-675-5p
;
hsa-mir-4466
;
hsa-mir-4749-5p
;
hsa-mir-4706
;
hsa-mir-202-3p
;
hsa-mir-1252-3p
;
hsa-mir-3646
;
hsa-let-7d-5p
;
hsa-let-7c-5p
;
hsa-mir-4500
;
hsa-mir-4458
;
hsa-let-7a-5p
;
hsa-let-7i-5p
;
hsa-let-7b-5p
;
hsa-let-7f-5p
;
hsa-mir-98-5p
;
hsa-let-7e-5p
;
hsa-let-7g-5p
;
hsa-mir-4446-5p
;
hsa-mir-524-5p
;
hsa-mir-520d-5p
;
hsa-mir-3189-5p
;
hsa-mir-4758-3p
;
hsa-mir-5699-5p
;
hsa-mir-324-3p
;
hsa-mir-1913
;
hsa-mir-6832-3p
;
hsa-mir-6756-3p
;
hsa-mir-3127-3p
;
hsa-mir-4726-3p
;
hsa-mir-6764-5p
;
hsa-mir-1915-3p
;
hsa-mir-6840-3p
;
hsa-mir-6729-3p
;
hsa-mir-346
;
hsa-mir-6516-5p
;
hsa-mir-510-3p
;
hsa-mir-5047
;
hsa-mir-1301-3p
;
hsa-mir-7156-3p
;
hsa-mir-6858-5p
;
hsa-mir-4689
;
hsa-mir-3915
;
hsa-mir-6867-3p
;
hsa-mir-6828-5p
;
hsa-mir-4660
;
hsa-mir-3928-3p
;
hsa-mir-494-3p
;
hsa-mir-302a-5p
;
hsa-mir-4685-3p
;
hsa-mir-7113-3p
;
hsa-mir-4287
;
hsa-mir-646
;
hsa-mir-1224-5p
;
hsa-mir-4469
;
hsa-mir-1233-5p
;
hsa-mir-1306-5p
;
hsa-mir-134-5p
;
hsa-mir-149-3p
;
hsa-mir-15a-5p
;
hsa-mir-16-5p
;
hsa-mir-195-5p
;
hsa-mir-3118
;
hsa-mir-3126-5p
;
hsa-mir-3136-5p
;
hsa-mir-3153
;
hsa-mir-3175
;
hsa-mir-424-5p
;
hsa-mir-4300
;
hsa-mir-4419a
;
hsa-mir-4439
;
hsa-mir-4510
;
hsa-mir-4513
;
hsa-mir-4723-5p
;
hsa-mir-4728-5p
;
hsa-mir-4796-3p
;
hsa-mir-497-5p
;
hsa-mir-5584-5p
;
hsa-mir-5591-5p
;
hsa-mir-5698
;
hsa-mir-597-3p
;
hsa-mir-6090
;
hsa-mir-6127
;
hsa-mir-6129
;
hsa-mir-6130
;
hsa-mir-6133
;
hsa-mir-6511a-3p
;
hsa-mir-6511b-3p
;
hsa-mir-6512-3p
;
hsa-mir-6720-5p
;
hsa-mir-6726-5p
;
hsa-mir-6733-5p
;
hsa-mir-6739-5p
;
hsa-mir-6778-5p
;
hsa-mir-6784-3p
;
hsa-mir-6785-5p
;
hsa-mir-6825-5p
;
hsa-mir-6827-5p
;
hsa-mir-6834-5p
;
hsa-mir-6838-5p
;
hsa-mir-6849-3p
;
hsa-mir-6855-3p
;
hsa-mir-6857-3p
;
hsa-mir-6862-3p
;
hsa-mir-6870-5p
;
hsa-mir-6875-5p
;
hsa-mir-6883-5p
;
hsa-mir-7111-5p
;
hsa-mir-7854-3p
;
hsa-mir-7855-5p
;
hsa-mir-920
;
hsa-mir-92a-1-5p
Nearest miRNA
hsa-mir-1244-3/Upstream/274629; hsa-let-7i/Downstream/1187476;
Nearest TSS
ENST00000382841/Upstream/2968;
ENST00000553174/Downstream/8658;
Nearest CpG islands
None/Target,
chr12-CpG: 104/Upstream/20157
,
chr12-CpG: 115/Downstream/13188
Upstream sequence
CTCAAGGCCCCAGGGCTCCACTGAAGATCCCAGTCTCCTTACCACTTGCACTTCCAGCCGCCCTTGGGGACGGTGAGCAGTGGGGGGTCCAGGCAGTATG
Downstream sequence
TGTGGTAGCTAATATCACAGTCATCACAGAGCAGCAGGCGTGAGGGGTCGGAGGCCTGGCCACACACCTCACACACAATACACTCCACACAACGCCAGCC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Jurkat CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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