Basic Information
VIS ID
TVIS30010324
Fusion event
HIV-MNAT1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
61283665/60816947 (Hg38)
End
61283665/60816947 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA14B
Target gene
MNAT1
miRNAs that regulate target gene
hsa-mir-26b-5p
Nearest miRNA
hsa-mir-208a/Upstream/168236; hsa-mir-1185-1/Downstream/3278077;
Nearest TSS
ENST00000550708/Upstream/4960; ENST00000525585/Downstream/164104;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/92893, chr14-CpG: 45/Downstream/163998
Nearest cancer related gene
MNAT1(OG, No orient, 0)
Upstream sequence
GTGCTTCAATATCAAAAGTGTTTTAGATCCTTAGAATGTTTGTTTTTATTAGATTTCAGCTGTTTACCAAGACACTTTAACATTCAGTTCCTTTTATGTG
Downstream sequence
AATGTGAAACCAGGATTAAAACAAGCTAAAGTCTTGACTAGCAACTTTTTTTTTGAAGTTAATACGTTGCTTTTATGTAAGAATTTTTGCTTTTTAAAGG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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