Basic Information
VIS ID
TVIS30010333
Fusion event
HIV-SEL1L integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
81940769/81474425 (Hg38)
End
81940769/81474425 (Hg38)
Orient
+
Location type
UTR3
Target gene
SEL1L
miRNAs that regulate target gene
hsa-mir-125b-5p ; hsa-mir-335-5p ; hsa-mir-155-5p ; hsa-mir-4668-5p ; hsa-mir-548as-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-19b-3p ; hsa-mir-19a-3p
Nearest miRNA
hsa-mir-1260a/Upstream/4208135; hsa-mir-1185-1/Downstream/12473801;
Nearest TSS
ENST00000550708/Upstream/24268; ENST00000554814/Downstream/10103;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/37622, chr14-CpG: 52/Downstream/58982
Upstream sequence
ACCAACAAACCAAATGCACAAGAGAATACTAAACAGGGTTTTACTGTCATCAAGTTCGAAGGCAGGAAGACAGACTAGAAAAGGTCTTAGGAGAGATGGG
Downstream sequence
CTACCATGGACAAATGAAGCCACACTCTATCTGTTAAATCTAAATTCTAACATTAAAACTCCTGAATCCTGGAGTTAGTTTAATGTCACTGACATTAACT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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