Basic Information
VIS ID
TVIS30010449
Fusion event
HIV-ADAMTS18 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
77363505/77329608 (Hg38)
End
77363505/77329608 (Hg38)
Orient
-
Location type
Intronic
Target gene
ADAMTS18
miRNAs that regulate target gene
hsa-mir-4680-5p ; hsa-mir-6823-5p ; hsa-mir-129-5p ; hsa-mir-6885-3p ; hsa-mir-6854-5p ; hsa-mir-599 ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-3161 ; hsa-mir-4684-5p ; hsa-mir-942-5p ; hsa-mir-1251-5p ; hsa-mir-517-5p ; hsa-mir-645 ; hsa-mir-3163 ; hsa-mir-3662 ; hsa-mir-130b-5p ; hsa-mir-4753-3p ; hsa-mir-7158-5p
Nearest miRNA
hsa-mir-1225/Upstream/460589; hsa-mir-11401/Downstream/4055410;
Nearest TSS
ENST00000527434/Upstream/8472; ENST00000564358/Downstream/101979;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/116492, chr16-CpG: 99/Downstream/104804
Nearest cancer related gene
ADAMTS18(TSG, No orient, 0)
Upstream sequence
gatccaacctttgtaaagaatgtagggcagtatctagggcagagtcagaataaataaattataactATTTTTAAATGCCTTATGCTTTTGTATTGAGTAC
Downstream sequence
CCACCCTGTGCTGAGTATTATGTGATCTGATTTTTATATACTAATACATTTCATTTTTAATTATGGGATATGGTCAAAGTGATCAAAAGTAATTGCTAGC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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