Basic Information
VIS ID
TVIS30010453
Fusion event
HIV-PIEZO1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
88842713/88776305 (Hg38)
End
88842713/88776305 (Hg38)
Orient
-
Location type
Intronic
Target gene
PIEZO1
miRNAs that regulate target gene
hsa-mir-10b-5p ; hsa-mir-940 ; hsa-mir-4665-5p ; hsa-mir-1275 ; hsa-mir-4472 ; hsa-mir-5010-5p ; hsa-mir-4447 ; hsa-mir-4525 ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-625-5p ; hsa-mir-3191-3p ; hsa-mir-92b-5p ; hsa-mir-885-3p ; hsa-mir-103a-3p
Nearest miRNA
hsa-mir-11401/Upstream/59968;
Nearest TSS
ENST00000527434/Upstream/33484; ENST00000562747/Downstream/8915;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/4254, chr16-CpG: 23/Downstream/2230
Upstream sequence
gggtggatcatgaggtcaggagattgagaccatcctggttaacacggtgaaaccccgtctctactaaaaatacaaaaaattagcggagtgtggtggtggg
Downstream sequence
cgcctgtagtcccagctactcgggaggctgaggaaggagaatggcgtgaacctgggaggcagagcttgcagtgagcccagactgggccactgcactccag
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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