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VISDB
Viral Integration Site DataBase
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TVIS30010480
Basic Information
VIS ID
TVIS30010480
Fusion event
HIV-MAP2K4 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p12
Reference genome
GRCh37/hg19
Start
11998637/12095320 (Hg38)
End
11998637/12095320 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA17A
Target gene
MAP2K4
miRNAs that regulate target gene
hsa-mir-375
;
hsa-mir-15b-5p
;
hsa-mir-26b-5p
;
hsa-mir-25-3p
;
hsa-mir-145-5p
;
hsa-mir-188-5p
;
hsa-mir-27a-3p
;
hsa-mir-92a-3p
;
hsa-mir-1185-2-3p
;
hsa-mir-1185-1-3p
;
hsa-let-7f-2-3p
;
hsa-mir-542-3p
;
hsa-mir-4261
;
hsa-mir-3134
;
hsa-mir-8082
;
hsa-mir-4534
;
hsa-mir-4433a-3p
;
hsa-mir-3688-3p
;
hsa-mir-6818-3p
;
hsa-mir-7855-5p
;
hsa-mir-4325
;
hsa-mir-7703
;
hsa-mir-6749-3p
;
hsa-mir-6792-3p
;
hsa-mir-4691-5p
;
hsa-mir-3185
;
hsa-mir-3121-5p
;
hsa-mir-660-3p
;
hsa-mir-5193
;
hsa-mir-3614-5p
;
hsa-mir-10a-3p
;
hsa-mir-559
;
hsa-mir-548y
;
hsa-mir-548w
;
hsa-mir-548o-5p
;
hsa-mir-548j-5p
;
hsa-mir-548i
;
hsa-mir-548h-5p
;
hsa-mir-548d-5p
;
hsa-mir-548c-5p
;
hsa-mir-548bb-5p
;
hsa-mir-548b-5p
;
hsa-mir-548ay-5p
;
hsa-mir-548au-5p
;
hsa-mir-548as-5p
;
hsa-mir-548ar-5p
;
hsa-mir-548aq-5p
;
hsa-mir-548ap-5p
;
hsa-mir-548am-5p
;
hsa-mir-548ak
;
hsa-mir-548ae-5p
;
hsa-mir-548ad-5p
;
hsa-mir-548ab
;
hsa-mir-548a-5p
;
hsa-mir-363-3p
;
hsa-mir-367-3p
;
hsa-mir-92b-3p
;
hsa-mir-32-5p
Nearest miRNA
hsa-mir-1253/Upstream/13324; hsa-mir-10226/Downstream/821948;
Nearest TSS
ENST00000595228/Upstream/25564;
ENST00000582377/Downstream/282;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/73766
,
chr17-CpG: 70/Downstream/570030
Nearest cancer related gene
MAP2K4
(TSG, No orient, 0)
Upstream sequence
TTATTCATATGAAACTGTTAAAACTCATTATCATTTTCTTTATATTTGCATGTGGGGGTTAATTTTTACTGCCTAAGAACTTTGTTGCATAACTCCCAAC
Downstream sequence
ATTATTAGTAAATGCTCATGGTTAAATTGCCCTGTCTCCTTTAAAGGATTTCTAAGTGCTGTTTGTTAAACTTTCTGTGATTAAAGTAATTCTTGTGAAG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Jurkat CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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