Basic Information
VIS ID
TVIS30010506
Fusion event
HIV-KPNB1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.32
Reference genome
GRCh37/hg19
Start
45760388/47683022 (Hg38)
End
45760388/47683022 (Hg38)
Orient
-
Location type
UTR3
Target gene
KPNB1
miRNAs that regulate target gene
hsa-mir-1296-5p ; hsa-mir-1236-3p ; hsa-mir-1229-3p ; hsa-mir-877-3p ; hsa-mir-744-5p ; hsa-mir-455-3p ; hsa-mir-766-3p ; hsa-mir-615-3p ; hsa-mir-484 ; hsa-mir-320a ; hsa-mir-149-5p ; hsa-mir-128-3p ; hsa-mir-125b-5p ; hsa-mir-222-3p ; hsa-mir-181b-5p ; hsa-mir-7-5p ; hsa-mir-92a-3p ; hsa-mir-30d-5p ; hsa-mir-566 ; hsa-mir-4496 ; hsa-mir-525-3p ; hsa-mir-524-3p ; hsa-mir-4484 ; hsa-mir-9-5p ; hsa-mir-2681-5p ; hsa-mir-581 ; hsa-mir-4455
Nearest miRNA
hsa-mir-1180/Upstream/709922; hsa-mir-10226/Downstream/349860;
Nearest TSS
ENST00000595228/Upstream/339; ENST00000578982/Downstream/11059;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/32166, chr17-CpG: 147/Downstream/10719
Upstream sequence
GGGTCAGGGATTTTTTACAGTCTGAGAATGAGTGTGTGTGAGTGAGGCGGTATCCACATTTTCAACTTCAAGTCATTGCAGTTTCTTTTTCCCAGAAAAC
Downstream sequence
AAGGGGTTAGATGTTGCATTTCATAAAACTAACCGAAGTTTTGTTTACTGATGCAGCACAAGAGATGTaaaaaaaaaaaaaaaaaaaaaaaaaaaaaCAC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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