Basic Information
VIS ID
TVIS30010546
Fusion event
HIV-SPIRE1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
p11.21
Reference genome
GRCh37/hg19
Start
12490261/12490262 (Hg38)
End
12490261/12490262 (Hg38)
Orient
+
Location type
Intronic
Target gene
SPIRE1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-151a-5p ; hsa-mir-186-5p ; hsa-mir-101-3p ; hsa-mir-769-5p ; hsa-mir-484 ; hsa-mir-99a-5p ; hsa-mir-218-5p ; hsa-mir-215-3p ; hsa-mir-6777-3p ; hsa-mir-3976 ; hsa-mir-369-3p ; hsa-mir-3123 ; hsa-mir-3925-5p ; hsa-mir-510-5p ; hsa-mir-4662a-3p ; hsa-mir-374c-5p ; hsa-mir-655-3p ; hsa-mir-181c-5p ; hsa-mir-181a-5p ; hsa-mir-181d-5p ; hsa-mir-4262 ; hsa-mir-181b-5p
Nearest miRNA
hsa-mir-3976/Upstream/835321; hsa-mir-1-2/Downstream/969685;
Nearest TSS
ENST00000575820/Upstream/35756; ENST00000400512/Downstream/2887;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/55775, chr18-CpG: 198/Downstream/166783
Upstream sequence
CAATTCTGGTGGTTGTGAAATACCAATTGTCAAGGTTAAAATAAAGACATACTTAACATAAAAATGTTATTTAATTATTCTAAAGTAGGGTTCCCATTAG
Downstream sequence
CAACTACATATAATTTTAAAAAGTGAAACTGAAGAATATGGCTTGCTATGAgagattgaatcactcatcaaaaagctccccaacaaaggcaggttcagga
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate