Basic Information
VIS ID
TVIS30010567
Fusion event
HIV-POLRMT integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
626763/626763 (Hg38)
End
626763/626763 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
POLRMT
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-30e-5p ; hsa-mir-30b-5p ; hsa-mir-92a-3p
Nearest miRNA
hsa-mir-1302-11/Upstream/554653; hsa-let-7e/Downstream/178177;
Nearest TSS
ENST00000633603/Upstream/1254; ENST00000591390/Downstream/3406;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/3258, chr19-CpG: 89/Downstream/5934
Upstream sequence
ggctcatgcctgtgctccctccactaaaaatacaaaaaaaaaaaaaaattagctgggcgtggtggcacatgcctgtaatctcagctactgggagcctggg
Downstream sequence
gcaggagaatcacttgaacgcagaaagcggaaattgcggtaagccgggatctcaccactgcactccagcctgggagacagaAACTTTGCTGTCGACAGAC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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