Basic Information
VIS ID
TVIS30010568
Fusion event
HIV-STK11 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
1210672/1210673 (Hg38)
End
1210672/1210673 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
STK11
miRNAs that regulate target gene
hsa-mir-130b-3p ; hsa-mir-93-5p ; hsa-mir-17-5p ; hsa-mir-199a-3p ; hsa-mir-6795-5p ; hsa-mir-6887-5p ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-6825-5p ; hsa-mir-6829-5p ; hsa-mir-6785-5p ; hsa-mir-6883-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-604 ; hsa-mir-4721 ; hsa-mir-6890-3p ; hsa-mir-4446-3p ; hsa-mir-4767 ; hsa-mir-873-5p ; hsa-mir-3141 ; hsa-mir-7-5p ; hsa-mir-150-5p ; hsa-mir-3943 ; hsa-mir-4530 ; hsa-mir-4660 ; hsa-mir-4715-3p ; hsa-mir-4722-3p ; hsa-mir-500b-3p ; hsa-mir-646 ; hsa-mir-6727-3p ; hsa-mir-6736-3p ; hsa-mir-6752-3p ; hsa-mir-6801-3p ; hsa-mir-6810-3p ; hsa-mir-6856-3p
Nearest miRNA
hsa-mir-1302-11/Upstream/397020; hsa-let-7e/Downstream/605486;
Nearest TSS
ENST00000633603/Upstream/3582; ENST00000591133/Downstream/9340;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/3250, chr19-CpG: 29/Downstream/9813
Nearest cancer related gene
STK11(TSG, No orient, 0)
Upstream sequence
TGAGTTAAAAAGAGggctgggcatgttcggtcatgcctgtaatcccagcactttgggaggccaaggcgggtggatcacccgaggttgggagttagcctga
Downstream sequence
ccaacatggtgaaaccctgtctctactaaaaatacaaaattagctgagtgtggtggcgcacgcctgtaatcccagctactctggaggctgaggcaggaga
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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