Basic Information
VIS ID
TVIS30010570
Fusion event
HIV-PWWP3A integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
1358657/1358658 (Hg38)
End
1358657/1358658 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
PWWP3A
miRNAs that regulate target gene
hsa-mir-1199-5p ; hsa-mir-1225-3p ; hsa-mir-1233-3p ; hsa-mir-125a-5p ; hsa-mir-125b-5p ; hsa-mir-1324 ; hsa-mir-3943 ; hsa-mir-4313 ; hsa-mir-4319 ; hsa-mir-574-3p ; hsa-mir-6751-3p ; hsa-mir-6847-3p
Nearest miRNA
hsa-mir-1302-11/Upstream/545005; hsa-let-7e/Downstream/457501;
Nearest TSS
ENST00000633603/Upstream/2268; ENST00000586996/Downstream/3238;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/3307, chr19-CpG: 23/Downstream/1381
Nearest cancer related gene
PWWP3A(OG, No orient, 0)
Upstream sequence
CCTGTTCACCATGTTTTTCTTCATACAAGGGAACGCGAATCCCCTGAGCTGAAGGAGAAGGAAAAATGGATCCGCTTTCTTAAACCTTTCCAGAATTTGC
Downstream sequence
CCCTAGAACCACTCCTATTCTTGACGCCCAGAATGGTCAGTGGTGAGCATCAAGGTCATCTCGTACCCCCGTGGCCTCCAGTACACAAGACGAGGAAGGA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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