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Viral Integration Site DataBase
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TVIS30010588
Basic Information
VIS ID
TVIS30010588
Fusion event
HIV-DNM2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
10832074/10721398 (Hg38)
End
10832074/10721398 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
DNM2
miRNAs that regulate target gene
hsa-mir-124-3p
;
hsa-mir-130a-3p
;
hsa-mir-615-3p
;
hsa-mir-92a-3p
;
hsa-mir-6875-5p
;
hsa-mir-6809-5p
;
hsa-mir-765
;
hsa-mir-711
;
hsa-mir-4784
;
hsa-mir-4708-3p
;
hsa-mir-3150b-3p
;
hsa-mir-6840-3p
;
hsa-mir-665
;
hsa-mir-4459
;
hsa-mir-4761-3p
;
hsa-mir-7843-5p
;
hsa-mir-6879-5p
;
hsa-mir-6735-5p
;
hsa-mir-4632-5p
;
hsa-mir-4436b-3p
;
hsa-mir-6859-5p
;
hsa-mir-3916
;
hsa-mir-3125
Nearest miRNA
hsa-mir-1181/Upstream/2895; hsa-let-7e/Downstream/58856;
Nearest TSS
ENST00000633603/Upstream/2837;
ENST00000588976/Downstream/33723;
Nearest CpG islands
None/Target,
chr19-CpG: 112/Upstream/2734
,
chr19-CpG: 70/Downstream/114442
Upstream sequence
ggcgcgcgttaccacacccggctaatttttgtatttttagcagagatggggtttcaccatgttggccaggctggtcttgaactcctgacctcaggtgatc
Downstream sequence
cgcccacctcggccacccaaaatgctggcattaaaggtgtgaaccaccatggctggccTCGTTAAGAGTATTAATTCAGTACCTGAAAGCCAAAGTTGTA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Jurkat CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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