Basic Information
VIS ID
TVIS30010589
Fusion event
HIV-DNM2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
10850674/10739998 (Hg38)
End
10850674/10739998 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
DNM2
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-130a-3p ; hsa-mir-615-3p ; hsa-mir-92a-3p ; hsa-mir-6875-5p ; hsa-mir-6809-5p ; hsa-mir-765 ; hsa-mir-711 ; hsa-mir-4784 ; hsa-mir-4708-3p ; hsa-mir-3150b-3p ; hsa-mir-6840-3p ; hsa-mir-665 ; hsa-mir-4459 ; hsa-mir-4761-3p ; hsa-mir-7843-5p ; hsa-mir-6879-5p ; hsa-mir-6735-5p ; hsa-mir-4632-5p ; hsa-mir-4436b-3p ; hsa-mir-6859-5p ; hsa-mir-3916 ; hsa-mir-3125
Nearest miRNA
hsa-mir-1181/Upstream/21495; hsa-let-7e/Downstream/40256;
Nearest TSS
ENST00000633603/Upstream/21437; ENST00000588976/Downstream/15123;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/21334, chr19-CpG: 70/Downstream/95842
Upstream sequence
tgaagccacctgggcctggacttttctttgtgggacgttttttgaatactaattaaatttcttgtacatctattgagtttttctgtgtcttcttgagtca
Downstream sequence
gtttcagtaatttgggtctttctaggaatttgtccatttcatctagggtgtatttaatttgttagaatagtattcccttatcatcttttttatttctgaa
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate