Basic Information
VIS ID
TVIS30010610
Fusion event
HIV-HNRNPL integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
39330094/38839454 (Hg38)
End
39330094/38839454 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
HNRNPL
miRNAs that regulate target gene
hsa-mir-193b-3p ; hsa-mir-183-5p ; hsa-mir-877-3p ; hsa-mir-615-3p ; hsa-mir-324-5p ; hsa-mir-328-3p ; hsa-mir-106b-5p ; hsa-mir-186-5p ; hsa-mir-23b-3p ; hsa-mir-16-5p ; hsa-let-7b-5p ; hsa-mir-4719 ; hsa-mir-6721-5p ; hsa-mir-4802-3p ; hsa-mir-942-3p ; hsa-mir-587 ; hsa-mir-3180-5p ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-6854-3p ; hsa-mir-885-5p ; hsa-mir-4738-5p ; hsa-mir-6877-3p ; hsa-mir-6819-3p ; hsa-mir-7109-3p
Nearest miRNA
hsa-mir-10395/Upstream/3493827; hsa-let-7e/Downstream/570169;
Nearest TSS
ENST00000633603/Upstream/1869; ENST00000593830/Downstream/210;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/7520, chr19-CpG: 226/Downstream/9829
Upstream sequence
TCACAAGGTAAAATACTCCTTCAGCTGGGTTACAACagagcagtgccggctctggagccaggcagtctggctctgagtcctgcttcacataaaggctatg
Downstream sequence
tgaacctgggcgcgttatttaagccccgtcctccacttcccctgtccatctcattaaggattaatgtgagaaattacacaggtcactacatgtaaagcat
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate