Basic Information
VIS ID
TVIS30010644
Fusion event
HIV-ROCK2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p25.1
Reference genome
GRCh37/hg19
Start
11462722/11322596 (Hg38)
End
11462722/11322596 (Hg38)
Orient
+
Location type
Intronic
Target gene
ROCK2
miRNAs that regulate target gene
hsa-mir-138-5p ; hsa-mir-124-3p ; hsa-mir-142-3p ; hsa-mir-139-5p ; hsa-mir-200c-3p ; hsa-mir-200b-3p ; hsa-mir-203a-3p ; hsa-mir-5007-3p ; hsa-mir-380-3p ; hsa-mir-411-3p ; hsa-mir-379-3p ; hsa-mir-4495 ; hsa-mir-30b-5p ; hsa-mir-30c-5p ; hsa-mir-30e-5p ; hsa-mir-30d-5p ; hsa-mir-30a-5p ; hsa-mir-1277-5p ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-190a-3p ; hsa-mir-5695 ; hsa-mir-519d-5p ; hsa-mir-5011-5p ; hsa-mir-4455 ; hsa-mir-4789-5p ; hsa-mir-6867-5p ; hsa-mir-574-5p ; hsa-mir-511-3p ; hsa-mir-625-3p ; hsa-mir-135a-5p ; hsa-mir-144-5p
Nearest miRNA
hsa-mir-4261/Upstream/1129925; hsa-mir-10b/Downstream/218009;
Nearest TSS
ENST00000437798/Upstream/34859; ENST00000437795/Downstream/21545;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/166716, chr2-CpG: 181/Downstream/21237
Upstream sequence
AGAGCATCCATAATGCTCTTCTAATACTTCCAAAGCATGGTGACTGCCACCATTCTTAATTCAGGGTGTTTGTTATCTGCTGCTCAAATAGCAAGTAAGG
Downstream sequence
TATCATTTTATACTACTCTATTTATAGCTCTTTAATTCATCATTTAACTTTCCACTTGACAATAAGCTTTATCTTCCCAAACTATAACTTCTTAAAAGTA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate