Basic Information
VIS ID
TVIS30010653
Fusion event
HIV-ASB3 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p16.2
Reference genome
GRCh37/hg19
Start
53929578/53702441 (Hg38)
End
53929578/53702441 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2D ; FRA2H
Target gene
ASB3
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-935 ; hsa-mir-615-3p ; hsa-mir-30a-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-30e-5p ; hsa-mir-342-3p ; hsa-mir-1285-5p ; hsa-mir-193b-3p ; hsa-mir-193a-3p ; hsa-mir-204-3p ; hsa-mir-2681-5p ; hsa-mir-4646-5p ; hsa-mir-4747-5p ; hsa-mir-5196-5p ; hsa-mir-7849-3p
Nearest miRNA
hsa-mir-1301/Upstream/999826; hsa-mir-10b/Downstream/146681;
Nearest TSS
ENST00000437798/Upstream/7879; ENST00000295304/Downstream/63108;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1072455, chr2-CpG: 28/Downstream/65313
Upstream sequence
TGTGCACACTACAGAAACACAAGCAACTTCAACTTCAGGGCTCTATATGACCTTGATTATTACATGTCACTAAGCACACAATAAATCCTTGAGCATGGAT
Downstream sequence
AACCTCTGGTTAAAATATAAATTAGTATGTATTTCTCTTAACACTTCAACAAATTCTCTCTGTAGCCCTAATATCAAATTGAGAAAACTCTTCAAGTACC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate