Basic Information
VIS ID
TVIS30010662
Fusion event
HIV-EXOC6B integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
72958339/72731210 (Hg38)
End
72958339/72731210 (Hg38)
Orient
-
Location type
Exonic
Fragile sites / regions
FRA2S ; FRA2E
Target gene
EXOC6B
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-484 ; hsa-mir-331-3p ; hsa-mir-25-3p ; hsa-mir-7977 ; hsa-mir-6516-3p ; hsa-mir-6849-3p ; hsa-mir-5588-3p
Nearest miRNA
hsa-mir-1285-2/Upstream/2478205; hsa-mir-10b/Downstream/2359602;
Nearest TSS
ENST00000437798/Upstream/215456; ENST00000498749/Downstream/94795;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/581164, chr2-CpG: 63/Downstream/94298
Upstream sequence
AAAAAAATTACACCAAGAATCCTTCTCCATTTCCAGTTCCTCACCTGGAAGACACAGCATTAATTTATCAACAGTGGCAGAAATATTTCTCTGTTGTAGT
Downstream sequence
CGACACTGCTTCAGCTCTTCCATTGCTATTACCAGCTTGGCAAGAGGGAAAAAGACTGAATTATGCCTATGGCTGTAAATAAAAAGCTTTCAGTCACATT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate