Basic Information
VIS ID
TVIS30010665
Fusion event
HIV-IGK integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
90034000/89995190 (Hg38)
End
90034000/89995190 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2L
Target gene
IGK
Nearest miRNA
hsa-mir-1285-2/Upstream/1182736; hsa-mir-10b/Downstream/6803088;
Nearest TSS
ENST00000437798/Upstream/5203; ENST00000462693/Downstream/9607;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/227089, chr2-CpG: 65/Downstream/242858
Nearby gene
MIR4436A(No orient, 922032)
Upstream sequence
TGCACTTTTATTATTAGTCCATTATGGTTCTTATTTATTTATTCATATTTTTAGCACTCACTAATTCATTCATTAATATTAGTAATATAATAAATTCATG
Downstream sequence
TTACTATCCTGCAAAACAACCACTTAAGATATCAACATATCCAGTTTGAGGTTCTCCACAATCTCTTAAACATATTATTTCCCACCACCATCAAGTTAAT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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