Basic Information
VIS ID
TVIS30010667
Fusion event
HIV-REV1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
100045626/99429164 (Hg38)
End
100045626/99429164 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2A
Target gene
REV1
miRNAs that regulate target gene
hsa-mir-96-5p ; hsa-mir-21-5p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-155-5p
Nearest miRNA
hsa-mir-1285-2/Upstream/2630811; hsa-mir-10b/Downstream/1880286;
Nearest TSS
ENST00000437798/Upstream/4530; ENST00000434301/Downstream/9516;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/91227, chr2-CpG: 202/Downstream/59917
Upstream sequence
CACTTGCCAGCAATGTGTAAGGGCTTGCTGTGTGATATAGGTAAAAATGTCTGTGTTTGGTTGACAAGGAAAAAAAAATGAAGACTTCTCTTTTTAATTA
Downstream sequence
TTACTCCCTCTACTTTTACAACTATTCCAATTATTTCAAAACGGTTTTTTAAATTATGAGGAAGATATATATATATGAGTGTGTGTGTGTTTCTTCCTAT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate