Basic Information
VIS ID
TVIS30010668
Fusion event
HIV-MAP4K4 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
102317178/101700716 (Hg38)
End
102317178/101700716 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2A
Target gene
MAP4K4
miRNAs that regulate target gene
hsa-mir-520e ; hsa-mir-181a-5p ; hsa-mir-31-5p ; hsa-mir-141-3p ; hsa-mir-302c-5p ; hsa-mir-30d-5p ; hsa-let-7a-5p ; hsa-mir-5687
Nearest miRNA
hsa-mir-1285-2/Upstream/391182; hsa-mir-10b/Downstream/731573;
Nearest TSS
ENST00000437798/Upstream/2186; ENST00000489490/Downstream/96518;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/2350, chr2-CpG: 92/Downstream/441630
Upstream sequence
TCTTTTCCTCCTTTATTTTAATGTAAACCCCAAATGCTATTTCAGCTGTAAATACTTTAGAATGTTTCTTTTTTACACAATCACATTGTTGTTATCACAC
Downstream sequence
TTAGAAAAATGTCATATATTCACTATTAACGTTTTCTTGATTGTCTCATACATCAGTAAAATGTGTTTTTTTTTTTTTTTACTATAACAAGTTCTTTAAT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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