Basic Information
VIS ID
TVIS30010676
Fusion event
HIV-LRP1B integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
141963649/141206080 (Hg38)
End
141963649/141206080 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
LRP1B
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-26b-5p ; hsa-mir-200c-3p ; hsa-mir-106b-3p ; hsa-mir-5692a
Nearest miRNA
hsa-mir-128-1/Upstream/619395; hsa-mir-10b/Downstream/8124198;
Nearest TSS
ENST00000437798/Upstream/848012; ENST00000410015/Downstream/604321;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/2425000, chr2-CpG: 58/Downstream/924075
Nearest cancer related gene
LRP1B(TSG, No orient, 0)
Upstream sequence
GAGCAAACCATAGACTGGGCCTAATGAGGCACCTTGGAGAAAATATGGGAGTCTTTTAAGTGAATTGGTGATGCCAAGGAAAGATATGAAATTGTCAAAA
Downstream sequence
CCATACTATGACATAACTGTGAATAAAAATAATGTGAGGAAGTGTACTATTcacacacacacacacacacacacacacgcacaACCAGGAAGCCAGATCA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate