Basic Information
VIS ID
TVIS30010688
Fusion event
HIV-PPIL3 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q33.1
Reference genome
GRCh37/hg19
Start
201742386/200877663 (Hg38)
End
201742386/200877663 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2I
Target gene
PPIL3
miRNAs that regulate target gene
hsa-mir-664b-3p ; hsa-mir-579-3p ; hsa-mir-5696 ; hsa-mir-5007-3p ; hsa-mir-3144-3p ; hsa-mir-1185-2-3p ; hsa-mir-1185-1-3p ; hsa-let-7f-2-3p ; hsa-mir-4789-5p ; hsa-mir-98-3p ; hsa-let-7f-1-3p ; hsa-let-7b-3p ; hsa-let-7a-3p ; hsa-mir-466 ; hsa-mir-6853-3p ; hsa-mir-4670-3p ; hsa-mir-4729 ; hsa-mir-8060 ; hsa-mir-103b ; hsa-mir-5011-5p ; hsa-mir-875-5p ; hsa-mir-4643 ; hsa-mir-4789-3p
Nearest miRNA
hsa-mir-10b/Upstream/11744552; hsa-mir-1244-1/Downstream/5905571;
Nearest TSS
ENST00000437798/Upstream/12919; ENST00000454952/Downstream/4079;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/12809, chr2-CpG: 53/Downstream/85629
Upstream sequence
ATCTCTTCTCACATACAATGGACTCTTGCTagtttctttatctgtaaaacaagggaggctggactagTTCAAGGGTCTATTTATaactcagatgctcaca
Downstream sequence
agggtcaagcagataaactgacaattgggcagaatgtaaacattagagagagatgaagtctggcaaaatgaatagGCTATCTCTTGATTAATGACATTAA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate