Basic Information
VIS ID
TVIS30010702
Fusion event
HIV-PLCB1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
8435491/8454844 (Hg38)
End
8435491/8454844 (Hg38)
Orient
+
Location type
Intronic
Target gene
PLCB1
miRNAs that regulate target gene
hsa-mir-423-5p ; hsa-mir-30c-5p ; hsa-mir-297 ; hsa-mir-4325 ; hsa-mir-6867-5p ; hsa-mir-567 ; hsa-mir-223-5p ; hsa-mir-3607-5p ; hsa-mir-511-3p ; hsa-mir-502-3p ; hsa-mir-501-3p
Nearest miRNA
hsa-mir-103a-2/Upstream/1083152; hsa-mir-1-1/Downstream/2194792;
Nearest TSS
ENST00000382410/Upstream/83764; ENST00000637000/Downstream/145871;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/321899, chr20-CpG: 107/Downstream/613467
Upstream sequence
ctgggcagccttttaaaaattgcattgtttctctgtttccctgtcatgcctttcttttctctatagtatttatccccatctaacatattatatattttac
Downstream sequence
ttaccaattttattttcttctaaaatgtatatttcatgcatttttatctgttttgttcactgctttttagttcacatgtcttgaacgtggtctggtatac
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate