Basic Information
VIS ID
TVIS30010731
Fusion event
HIV-TIAM1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q22.11
Reference genome
GRCh37/hg19
Start
32751050/31378736 (Hg38)
End
32751050/31378736 (Hg38)
Orient
-
Location type
Intronic
Target gene
TIAM1
miRNAs that regulate target gene
hsa-mir-21-5p ; hsa-mir-31-5p ; hsa-mir-335-5p ; hsa-mir-744-5p ; hsa-mir-93-3p ; hsa-mir-769-3p ; hsa-mir-615-3p ; hsa-mir-221-3p ; hsa-let-7b-5p ; hsa-mir-10b-5p ; hsa-mir-329-3p ; hsa-mir-141-3p ; hsa-mir-10a-5p ; hsa-mir-342-3p ; hsa-mir-29c-3p ; hsa-mir-22-3p ; hsa-mir-182-5p
Nearest miRNA
hsa-let-7c/Upstream/1003358; hsa-mir-3197/Downstream/2171926;
Nearest TSS
ENST00000624081/Upstream/34457; ENST00000433071/Downstream/180241;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/34566, chr21-CpG: 248/Downstream/178878
Upstream sequence
TTCCCTGAAGACAATCTTTTTCCCACTCATACTCGCTGCCACACAATTTGGCCAAGAGagttggtcttcggtatccgtaggttctgcacccctgggttcc
Downstream sequence
accaactgcagatccaaaatattttaaaaaaggaaaaatagatggttgcactgcatccgtactgcatatgtacaggcttgttttgcttgtcactattccc
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate