Basic Information
VIS ID
TVIS30010744
Fusion event
HIV-GNB1L integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
19825747/19838224 (Hg38)
End
19825747/19838224 (Hg38)
Orient
-
Location type
Intronic
Target gene
GNB1L
miRNAs that regulate target gene
hsa-mir-6809-3p ; hsa-mir-4768-5p ; hsa-mir-6833-3p ; hsa-mir-4684-5p ; hsa-mir-7108-5p ; hsa-mir-6765-5p ; hsa-mir-663b ; hsa-mir-1294 ; hsa-mir-4316 ; hsa-mir-6087 ; hsa-mir-4252 ; hsa-mir-3197 ; hsa-mir-4677-3p ; hsa-mir-212-5p ; hsa-mir-6749-5p ; hsa-mir-5587-3p ; hsa-mir-5690 ; hsa-mir-4739 ; hsa-mir-4756-5p ; hsa-mir-1321 ; hsa-mir-4717-5p ; hsa-mir-3926 ; hsa-mir-1250-5p ; hsa-mir-3187-3p ; hsa-mir-4435 ; hsa-mir-4701-5p ; hsa-mir-4746-3p ; hsa-mir-548s ; hsa-mir-588
Nearest miRNA
hsa-mir-3198-1/Upstream/1857263; hsa-let-7a-3/Downstream/125529;
Nearest TSS
ENST00000624155/Upstream/73145; ENST00000467943/Downstream/16582;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/49293, chr22-CpG: 122/Downstream/16136
Upstream sequence
GCACAATCTATTTTTGTGCTCATTAAAGGAAATGCAAGagcaactaaacaatccaattaaaaaggcataaaagatttggccaaacactccacctaaaaag
Downstream sequence
atgtgcaaataagcacaaaaggcaactcaacatcatagccattagggaaatgcaacttatgcccataatgaaataccactacatacctactagagtggct
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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