Basic Information
VIS ID
TVIS30010781
Fusion event
HIV-KLHL18 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p21.31
Reference genome
GRCh37/hg19
Start
47338809/47297319 (Hg38)
End
47338809/47297319 (Hg38)
Orient
-
Location type
Intronic
Target gene
KLHL18
miRNAs that regulate target gene
hsa-mir-103a-3p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-92b-3p ; hsa-mir-545-3p ; hsa-mir-4514 ; hsa-mir-4692 ; hsa-mir-5191 ; hsa-mir-4673 ; hsa-mir-4645-5p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-4496 ; hsa-mir-6808-5p ; hsa-mir-4311 ; hsa-mir-4668-5p
Nearest miRNA
hsa-mir-12127/Upstream/2435338; hsa-let-7g/Downstream/552236;
Nearest TSS
ENST00000440867/Upstream/13868; ENST00000462998/Downstream/83680;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/14161, chr3-CpG: 33/Downstream/59002
Upstream sequence
TCGAAAACTGCAGACTGAGCCCAGTATGTTTTATTATACTTGCCATCAGTTTCTTAACCCCAAGAGTTTATGAGGACTCATCATTTCTGCTTGTGGTAGT
Downstream sequence
ACTATATGAACCTGTGTCTCTCTGTCCGTATTCTAGGCTGGCAGTCAGGCCATCAGCATTGAAGGTGAAAGAATCCCCCTGACTTCCATTTCCTTATATG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate