Basic Information
VIS ID
TVIS30010800
Fusion event
HIV-LRIG1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p14.1
Reference genome
GRCh37/hg19
Start
66534878/66484454 (Hg38)
End
66534878/66484454 (Hg38)
Orient
-
Location type
Intronic
Target gene
LRIG1
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-98-5p ; hsa-mir-149-5p ; hsa-mir-92a-3p ; hsa-let-7b-5p ; hsa-mir-4753-5p ; hsa-mir-218-5p ; hsa-mir-3187-3p ; hsa-mir-4435 ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-4764-3p ; hsa-mir-3926 ; hsa-mir-3140-3p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-5088-3p ; hsa-mir-4797-3p ; hsa-mir-545-5p ; hsa-mir-208b-5p ; hsa-mir-208a-5p ; hsa-mir-4652-3p ; hsa-mir-4743-3p ; hsa-mir-6888-3p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-5193 ; hsa-mir-660-3p ; hsa-mir-361-3p ; hsa-mir-589-3p
Nearest miRNA
hsa-let-7g/Upstream/5866584; hsa-mir-12124/Downstream/741010;
Nearest TSS
ENST00000440867/Upstream/15209; ENST00000460784/Downstream/13805;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/263162, chr3-CpG: 187/Downstream/15440
Nearest cancer related gene
LRIG1(TSG, No orient, 0)
Upstream sequence
aaagccagtcactgcattcagggagcttacagactaatggggtagtcagaaacgaatcaaacattcacacaaaacttctatacatagcactgcagaatcc
Downstream sequence
tcacgatgggaatctaacttaaagggaacgtcagccatggtttctatggggagaaacgtttaagacagatgaacagaaatctgcaaggcgaagagggaag
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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