Basic Information
VIS ID
TVIS30010824
Fusion event
HIV-EIF2A integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
150285168/150567381 (Hg38)
End
150285168/150567381 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA3D
Target gene
EIF2A
miRNAs that regulate target gene
hsa-mir-16-5p ; hsa-mir-186-5p ; hsa-mir-30c-5p ; hsa-mir-340-5p ; hsa-mir-218-5p ; hsa-mir-9-3p ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-100-3p ; hsa-mir-4429 ; hsa-mir-320d ; hsa-mir-320c ; hsa-mir-320b ; hsa-mir-320a ; hsa-mir-6878-3p ; hsa-mir-640 ; hsa-mir-203b-3p ; hsa-mir-7158-3p ; hsa-mir-378a-5p ; hsa-mir-6744-3p ; hsa-mir-4757-5p ; hsa-mir-6131 ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-4680-5p ; hsa-mir-4635 ; hsa-mir-3663-5p ; hsa-mir-3653-5p ; hsa-mir-212-5p ; hsa-mir-1224-3p ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-6813-3p
Nearest miRNA
hsa-let-7g/Upstream/16129475; hsa-mir-1224/Downstream/998495;
Nearest TSS
ENST00000440867/Upstream/15027; ENST00000472926/Downstream/18;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/20561, chr3-CpG: 71/Downstream/35834
Upstream sequence
AATTTCCATATCCACATTCTGCAGTAGCAGGCCAAGGTTGATCTTTTCCTTCTAATAGGCTCTAAGACCACTTTATTTCAGCGATTGAAGAGAGGataac
Downstream sequence
tgacatttatcaaatacctaccatgtgcctggcactcttctCTTAAAACCAATTACTGAGAGTTGGGTGGTATAATCCCATTacttgcctaagctcacac
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate