Basic Information
VIS ID
TVIS30010825
Fusion event
HIV-MED12L integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
150923376/151205589 (Hg38)
End
150923376/151205589 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA3D
Target gene
MED12L
miRNAs that regulate target gene
hsa-mir-93-5p ; hsa-mir-484 ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-580-5p ; hsa-mir-1468-3p ; hsa-mir-548f-5p ; hsa-mir-548g-5p ; hsa-mir-548x-5p ; hsa-mir-3662 ; hsa-mir-548aj-5p ; hsa-mir-4698 ; hsa-mir-548aw ; hsa-mir-6750-3p ; hsa-mir-6516-3p ; hsa-mir-4764-3p ; hsa-mir-3607-5p ; hsa-mir-32-3p ; hsa-mir-2276-3p ; hsa-mir-4772-3p ; hsa-mir-1306-5p
Nearest miRNA
hsa-let-7g/Upstream/16767683; hsa-mir-1224/Downstream/360287;
Nearest TSS
ENST00000440867/Upstream/2388; ENST00000468305/Downstream/36207;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/118208, chr3-CpG: 92/Downstream/1062949
Upstream sequence
ACTTGCTTTGAATATTTAGCGTTTTTAAAATGTGCTTTTTCGGCATAGCATGGAAGCCATTTGGAACTAATGAGGAAGGGGAAAGCAAATGTTGGGGTCG
Downstream sequence
GTGGTCACTGCCACAGCCGGGCACAGGTCTGAGGacttgtttttgttaaaacaagccatgagatacaggagattctgcctcttacagatggggaaactgt
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate