Basic Information
VIS ID
TVIS30010877
Fusion event
HIV-EMB integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q11.1
Reference genome
GRCh37/hg19
Start
49727175/50431341 (Hg38)
End
49727175/50431341 (Hg38)
Orient
+
Location type
Intronic
Target gene
EMB
miRNAs that regulate target gene
hsa-mir-192-5p ; hsa-mir-151a-3p ; hsa-mir-10a-5p ; hsa-mir-218-5p ; hsa-mir-6513-5p ; hsa-mir-5089-5p ; hsa-mir-6728-5p ; hsa-mir-769-3p ; hsa-mir-450b-3p ; hsa-mir-1296-5p ; hsa-mir-4425 ; hsa-mir-3147 ; hsa-mir-4468 ; hsa-mir-2861 ; hsa-mir-4781-3p ; hsa-mir-4512 ; hsa-mir-7160-3p ; hsa-mir-6895-5p ; hsa-mir-646 ; hsa-mir-576-3p ; hsa-mir-7-2-3p ; hsa-mir-7-1-3p ; hsa-mir-5688 ; hsa-mir-495-3p ; hsa-mir-514b-5p ; hsa-mir-513c-5p ; hsa-mir-4796-5p ; hsa-mir-1250-3p ; hsa-mir-8084
Nearest miRNA
hsa-mir-10397/Upstream/11873780; hsa-mir-103a-1/Downstream/3520163;
Nearest TSS
ENST00000502646/Upstream/2614; ENST00000513414/Downstream/10009;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/4734933, chr5-CpG: 79/Downstream/9432
Upstream sequence
GCCTTAAGTGGAAAAGCAGGGCAACCTACAGAAGGTATTAGGACAGTAAAAGAAGTTCTTTGTTTAGGCAAGATTTTTTTAACCAAAAAAGTGAGAATGT
Downstream sequence
AAACCTTATTGCTTTCAGTTGGAGGACAGCTGGCAGGAGGCTGATTCAGCTAACATTGGGGTTTAAAGGAAATTGGCAGGAGACTCAGGCAGATGTGGTT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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