Basic Information
VIS ID
TVIS30010918
Fusion event
HIV-LMAN2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q35.3
Reference genome
GRCh37/hg19
Start
176776347/177349346 (Hg38)
End
176776347/177349346 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA5G
Target gene
LMAN2
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-99a-5p ; hsa-let-7b-5p ; hsa-mir-4668-5p ; hsa-mir-374b-5p ; hsa-mir-374a-5p ; hsa-mir-4783-3p ; hsa-mir-23a-3p ; hsa-mir-23c ; hsa-mir-130a-5p ; hsa-mir-23b-3p ; hsa-mir-6739-3p ; hsa-mir-4677-5p ; hsa-mir-7156-5p ; hsa-mir-4273 ; hsa-mir-22-5p ; hsa-mir-2116-5p
Nearest miRNA
hsa-mir-10397/Upstream/719846; hsa-mir-1229/Downstream/2448932;
Nearest TSS
ENST00000502646/Upstream/10802; ENST00000504631/Downstream/2176;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/11805, chr5-CpG: 41/Downstream/2225
Upstream sequence
CTGCTCAGAAGACAGCAGGTGTTCAGGGAATGTTCGCCTGAGTGCATGCCTCTCCCGGATGGAGTGAATGAAGGAGATAAAAAAGGGAAAAGTTTAGGAA
Downstream sequence
GCATCTCTCCAGCTCATTAAAGGAAGAGGCAGTTCTTGGGAAACACTGAACAGAAAATTCTGATTTCCAAGCCATTTCTTTCCAGAGTTTACAGGAAGCA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate