Basic Information
VIS ID
TVIS30011004
Fusion event
HIV-CCT6A integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
56129439/56061746 (Hg38)
End
56129439/56061746 (Hg38)
Orient
+
Location type
splicing
Fragile sites / regions
FRA7A
Target gene
CCT6A
miRNAs that regulate target gene
hsa-mir-32-5p ; hsa-mir-324-3p ; hsa-mir-30e-5p ; hsa-mir-186-5p ; hsa-mir-149-5p ; hsa-mir-18a-5p ; hsa-mir-17-5p ; hsa-mir-3663-3p ; hsa-mir-148a-3p ; hsa-mir-130a-3p ; hsa-mir-152-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-148b-3p ; hsa-mir-454-3p ; hsa-mir-301b-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-4789-5p ; hsa-mir-6516-5p ; hsa-mir-3942-3p ; hsa-mir-455-3p ; hsa-mir-5100 ; hsa-mir-676-5p ; hsa-mir-892c-5p ; hsa-mir-4276 ; hsa-mir-625-3p ; hsa-mir-8084 ; hsa-mir-548c-3p
Nearest miRNA
hsa-mir-1183/Upstream/11179946; hsa-mir-10399/Downstream/894039;
Nearest TSS
ENST00000635602/Upstream/68; ENST00000466479/Downstream/873;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/9476, chr7-CpG: 44/Downstream/2339
Upstream sequence
GAGAttttctttttcttttttcttttttttttttttttttttttttttACTATCAGTTATTAGTTCCTGTTTTCTCAAGAATTAAATTTGTTTACTTTAG
Downstream sequence
GTTCTTGCTCAGAACTCTGGTTTTGACCTTCAGGAAACATTAGTTAAAATTCAAGCAGAACATTCAGAATCAGGTCAGCTTGTGGGTGTGGACCTGAACA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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