Basic Information
VIS ID
TVIS30011005
Fusion event
HIV-MDH2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q11.23
Reference genome
GRCh37/hg19
Start
75695897/76066579 (Hg38)
End
75695897/76066579 (Hg38)
Orient
-
Location type
UTR3
Fragile sites / regions
FRA7J
Target gene
MDH2
miRNAs that regulate target gene
hsa-mir-1301-3p ; hsa-mir-615-3p ; hsa-mir-193b-3p ; hsa-mir-484 ; hsa-mir-425-3p ; hsa-mir-320a ; hsa-mir-27b-3p ; hsa-mir-222-3p ; hsa-mir-1251-3p ; hsa-mir-1322 ; hsa-mir-193a-3p ; hsa-mir-205-5p ; hsa-mir-337-5p ; hsa-mir-4297 ; hsa-mir-4477b ; hsa-mir-4496 ; hsa-mir-455-3p ; hsa-mir-4738-3p ; hsa-mir-5190 ; hsa-mir-532-5p ; hsa-mir-5581-5p ; hsa-mir-6499-3p ; hsa-mir-651-3p ; hsa-mir-6516-5p
Nearest miRNA
hsa-mir-10525/Upstream/151310; hsa-mir-10399/Downstream/16137436;
Nearest TSS
ENST00000635602/Upstream/6211; ENST00000479294/Downstream/135321;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/18130, chr7-CpG: 39/Downstream/83731
Upstream sequence
AAACTTTGTATTTTAATTTGCTTTGGTGATGATTACTGTATTGACATCATCATGCCTTCCAAATTGTGGGTGGCTCTGTGGGCGCATCAATAAAAGCCGT
Downstream sequence
CCTTGATTTTATTTTTCAAGGTCCCTTCTGTAAATGCTGTGCTTTCTTCCCTGTGAGAGCCAACTTTAGAGTGTCTGCTACCTCTTCATTACCAATCAGA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate