Basic Information
VIS ID
TVIS30011010
Fusion event
HIV-CUX1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
101677452/102034172 (Hg38)
End
101677452/102034172 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA7F
Target gene
CUX1
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-877-3p ; hsa-mir-455-3p ; hsa-mir-18b-5p ; hsa-mir-92a-3p ; hsa-let-7b-5p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-10525/Upstream/874617; hsa-mir-10399/Downstream/258931;
Nearest TSS
ENST00000635602/Upstream/74782; ENST00000485792/Downstream/63306;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/117827, chr7-CpG: 66/Downstream/161279
Nearest cancer related gene
CUX1(OG, No orient, 0)
Upstream sequence
caggcggaggttgcggtgagctgagatcatgccactggactccagcccaggtgacagagcgagactccatctcaaaaaaaaaaaaaaaaaaaaaagtcag
Downstream sequence
tcttattattgaataaatacacagaagtcttttcaaaggtattagtaaattaagtccatcaagcttggtatatcccaagaaggctgttttgtttaaaatg
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate