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Viral Integration Site DataBase
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TVIS30011056
Basic Information
VIS ID
TVIS30011056
Fusion event
HIV-PLEKHF2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
96162700/95150472 (Hg38)
End
96162700/95150472 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA8B
Target gene
PLEKHF2
miRNAs that regulate target gene
hsa-mir-124-3p
;
hsa-mir-215-5p
;
hsa-mir-192-5p
;
hsa-mir-103a-3p
;
hsa-mir-107
;
hsa-mir-20b-3p
;
hsa-mir-3688-3p
;
hsa-mir-3978
;
hsa-mir-4671-3p
;
hsa-mir-4694-3p
;
hsa-mir-4703-3p
;
hsa-mir-1183
;
hsa-mir-1304-5p
;
hsa-mir-1277-5p
;
hsa-mir-5582-5p
;
hsa-mir-6505-5p
;
hsa-mir-19a-3p
;
hsa-mir-19b-3p
;
hsa-mir-130a-3p
;
hsa-mir-301a-3p
;
hsa-mir-130b-3p
;
hsa-mir-454-3p
;
hsa-mir-301b-3p
;
hsa-mir-4295
;
hsa-mir-3666
;
hsa-mir-548aw
;
hsa-mir-6516-5p
;
hsa-mir-5047
;
hsa-mir-1301-3p
;
hsa-mir-7156-3p
;
hsa-mir-1468-3p
;
hsa-mir-548x-5p
;
hsa-mir-548g-5p
;
hsa-mir-548f-5p
;
hsa-mir-548aj-5p
;
hsa-mir-522-3p
;
hsa-mir-224-3p
;
hsa-mir-7161-5p
;
hsa-mir-548u
;
hsa-mir-4482-3p
;
hsa-mir-7159-3p
;
hsa-mir-6765-5p
;
hsa-mir-1827
;
hsa-mir-4461
;
hsa-mir-154-5p
;
hsa-mir-6882-5p
;
hsa-mir-3912-3p
Nearest miRNA
hsa-mir-12123/Upstream/77476; hsa-mir-10400/Downstream/3243173;
Nearest TSS
ENST00000518652/Upstream/16396;
ENST00000517655/Downstream/53984;
Nearest CpG islands
None/Target,
chr8-CpG: 109/Upstream/15971
,
chr8-CpG: 74/Downstream/118144
Upstream sequence
CACAACCCACCAATCAATCAAGTGGGCTGCCAGAATCATTAAAATAAATGAAGATAAAAGAATGCATCATTCATTGTTGAAATAATTATACGAGTGTTTG
Downstream sequence
TAACCTTGCAATATAAAATGTGTTTATGTTGGTCATTGTCAAACTTTGAAAGCTATTTGCTTTGCTGCAGCCAAATACTAATTAATAATGCCCCAAACCT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Jurkat CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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