Basic Information
VIS ID
TVIS30011061
Fusion event
HIV-EMC2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
109498761/108486532 (Hg38)
End
109498761/108486532 (Hg38)
Orient
-
Location type
Exonic
Target gene
EMC2
miRNAs that regulate target gene
hsa-mir-186-5p ; hsa-mir-6514-3p ; hsa-mir-6771-5p ; hsa-mir-425-3p ; hsa-mir-7977 ; hsa-mir-6811-3p ; hsa-mir-214-5p ; hsa-mir-6746-5p ; hsa-mir-338-3p ; hsa-mir-7157-5p ; hsa-mir-4310 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-6847-3p ; hsa-mir-194-3p ; hsa-mir-5693
Nearest miRNA
hsa-mir-12123/Upstream/4002067; hsa-mir-10400/Downstream/4156961;
Nearest TSS
ENST00000518652/Upstream/12681; ENST00000521504/Downstream/94530;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/42498, chr8-CpG: 36/Downstream/300668
Upstream sequence
TAACAGTGTGAAGATTGTCATTTTTAACCTGCCACTGAAATTGAGCCTAATTGAGCtttttttttttttttttaattaGTTTGCAGGTCGAAGTAAGAAG
Downstream sequence
GAAACCAAATATTCTCTTAAGGCTGTCGAAGACATGTTGGAAACATTGCAGATCACCCAGTCTTAAGGTTTCAAAAACTCTTTGACATTAGATTTCACAA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate